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An engineered selenocysteine defines a unique class of antibody derivatives
Selenocysteine is cotranslationally inserted into proteins by recoding the stop codon UGA from termination to selenocysteine insertion. The nucleophilic selenol group of selenocysteine endows this rare amino acid with unique chemical reactivity that allows regiospecific covalent conjugation in the p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518826/ https://ncbi.nlm.nih.gov/pubmed/18719095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800800105 |
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