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Molecularly defined antibody conjugation through a selenocysteine interface
Antibody conjugates have broad utility in basic, preclinical, and clinical applications. Conventional antibody conjugation through the amine group of lysine or the thiol group of cysteine residues yields heterogeneous products of undefined stoichiometry and considerable batch-to-batch variability. T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825887/ https://ncbi.nlm.nih.gov/pubmed/19894757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901744t |
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