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Haploinsufficiency of the maspin tumor suppressor gene leads to hyperplastic lesions in prostate

Maspin is a key tumor suppressor gene in prostate and breast with diverse biological functions. However, how maspin regulates prostate tumor progression is not fully understood. In this study, we have used maspin heterozygous knockout mouse to determine the effect of maspin haploinsufficiency on pro...

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Detalhes bibliográficos
Main Authors: Shao, Long-jiang, Shi, Heidi Y., Ayala, Gustavo, Rowley, David, Zhang, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518316/
https://ncbi.nlm.nih.gov/pubmed/18593913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0163
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