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Smad3 as a mediator of the fibrotic response
Transforming growth factor-β (TGF-β) plays a central role in fibrosis, contributing to the influx and activation of inflammatory cells, the epithelial to mesenchymal transdifferentiation (EMT) of cells and the influx of fibroblasts and their subsequent elaboration of extracellular matrix. TGF-β sign...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517464/ https://ncbi.nlm.nih.gov/pubmed/15154911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2004.00377.x |
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