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BRCA1 Interacts with Smad3 and Regulates Smad3-Mediated TGF-β Signaling during Oxidative Stress Responses

BACKGROUND: BRCA1 is a key regulatory protein participating in cell cycle checkpoint and DNA damage repair networks. BRCA1 plays important roles in protecting numerous cellular processes in response to cell damaging signals. Transforming growth factor-beta (TGF-β) is a potent regulator of growth, ap...

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Detalhes bibliográficos
Main Authors: Li, Huchun, Sekine, Masayuki, Seng, Seyha, Avraham, Shalom, Avraham, Hava Karsenty
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740868/
https://ncbi.nlm.nih.gov/pubmed/19768112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007091
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