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The Role of Smad3 in the Fibrotic Phenotype in Human Vocal Fold Fibroblasts

OBJECTIVE: To investigate the role of Smad3 as a regulator of transforming growth factor (TGF)-β1-mediated cell activities associated with fibrosis in normal human vocal fold fibroblasts. We also sought to confirm the temporal stability of Smad3 knockdown via siRNA. Vocal fold fibroblasts were emplo...

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Bibliographic Details
Published in:Laryngoscope
Main Authors: Branski, Ryan C., Bing, Renjie, Kraja, Iv, Amin, Milan R.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814357/
https://ncbi.nlm.nih.gov/pubmed/26422444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.25673
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