Aging Enhances Indirect Flight Muscle Fiber Performance yet Decreases Flight Ability in Drosophila

We investigated the effects of aging on Drosophila melanogaster indirect flight muscle from the whole organism to the actomyosin cross-bridge. Median-aged (49-day-old) flies were flight impaired, had normal myofilament number and packing, barely longer sarcomeres, and slight mitochondrial deteriorat...

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Détails bibliographiques
Auteurs principaux: Miller, Mark S., Lekkas, Panagiotis, Braddock, Joan M., Farman, Gerrie P., Ballif, Bryan A., Irving, Thomas C., Maughan, David W., Vigoreaux, Jim O.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2008
Sujets:
Muscle and Contractility
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517049/
https://ncbi.nlm.nih.gov/pubmed/18515368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130005
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