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Intrinsic disorder and multiple phosphorylations constrain the evolution of the flightin N-terminal region

Flightin is a myosin binding phosphoprotein that originated in the ancestor to Pancrustacea ~500 MYA. In Drosophila melanogaster, flightin is essential for length determination and flexural rigidity of thick filaments. Here, we show that among 12 Drosophila species, the N-terminal region is characte...

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Detalhes bibliográficos
Publicado no:J Proteomics
Main Authors: Lemas, Dominick, Lekkas, Panagiotis, Ballif, Bryan A., Vigoreaux, Jim O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762717/
https://ncbi.nlm.nih.gov/pubmed/26691840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2015.12.006
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