Aging Enhances Indirect Flight Muscle Fiber Performance yet Decreases Flight Ability in Drosophila

We investigated the effects of aging on Drosophila melanogaster indirect flight muscle from the whole organism to the actomyosin cross-bridge. Median-aged (49-day-old) flies were flight impaired, had normal myofilament number and packing, barely longer sarcomeres, and slight mitochondrial deteriorat...

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Detalhes bibliográficos
Main Authors: Miller, Mark S., Lekkas, Panagiotis, Braddock, Joan M., Farman, Gerrie P., Ballif, Bryan A., Irving, Thomas C., Maughan, David W., Vigoreaux, Jim O.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Muscle and Contractility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517049/
https://ncbi.nlm.nih.gov/pubmed/18515368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130005
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