The Major Chemical-detoxifying System of UDP-glucuronosyltransferases Requires Regulated Phosphorylation Supported by Protein Kinase C

Finding rapid, reversible down-regulation of human UDP-glucuronosyltransferases (UGTs) in LS180 cells following curcumin treatment led to the discovery that UGTs require phosphorylation. UGTs, distributed primarily in liver, kidney, and gastrointestinal tract, inactivate aromatic-like metabolites an...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Basu, Nikhil K., Kole, Labanyamoy, Basu, Mousumi, Chakraborty, Kushal, Mitra, Partha S., Owens, Ida S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Enzyme Catalysis and Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516997/
https://ncbi.nlm.nih.gov/pubmed/18556656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800032200
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker