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Src supports UDP-glucuronosyltransferase-2B7 detoxification of catechol estrogens associated with breast cancer
Mammary gland-distributed and ER-bound UDP-glucuronosyltransferase(UGT)-2B7 metabolizes genotoxic catechol-estrogens (CE) associated with breast cancer initiation. Although UGT2B7 has 3 PKC- and 2 tyrosine kinase (TK)-sites, its inhibition by genistein, herbimycin-A and PP2 with parallel losses in p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710978/ https://ncbi.nlm.nih.gov/pubmed/19289110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.03.054 |
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