Phosphorylation of a UDP-glucuronosyltransferase regulates substrate specificity

UDP-glucuronosyltransferase (UGT) isozymes catalyze detoxification of numerous chemical toxins present in our daily diet and environment by conjugation to glucuronic acid. The special properties and enzymatic mechanism(s) that enable endoplasmic reticulum-bound UGT isozymes to convert innumerable st...

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Detalhes bibliográficos
Main Authors: Basu, Nikhil K., Kovarova, Martina, Garza, Amanda, Kubota, Shigeki, Saha, Tapas, Mitra, Partha S., Banerjee, Rajat, Rivera, Juan, Owens, Ida S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088353/
https://ncbi.nlm.nih.gov/pubmed/15845768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407872102
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