Targeted Inhibition of Glucuronidation Markedly Improves Drug Efficacy in Mice- a Model

Finding UDP-glucuronosyltransferases (UGT) require protein kinase C-mediated phosphorylation is important information that allows manipulation of this critical system. UGTs glucuronidate numerous aromatic-like chemicals derived from metabolites, diet, environment and, inadvertently, therapeutics to...

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Bibliographic Details
Main Authors: Basu, Nikhil K., Kole, Labanyamoy, Basu, Mousumi, McDonagh, Antony F., Owens, Ida S.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034522/
https://ncbi.nlm.nih.gov/pubmed/17586469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.05.224
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