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Regulation of Cardiac Specific nkx2.5 Gene Activity by Small Ubiquitin-like Modifier

The cardiac specific homeobox gene nkx2.5, a member of the nk-2 class family, plays a central role in cardiogenesis and is a target of the small ubiquitin-like modifier (SUMO). Nkx2.5 was modified by SUMO on its 51st amino acid, a lysine residue conserved across species but absent in other nk-2 memb...

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Bibliografiske detaljer
Main Authors: Wang, Jun, Zhang, Hua, Iyer, Dinakar, Feng, Xin-Hua, Schwartz, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516993/
https://ncbi.nlm.nih.gov/pubmed/18579533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709748200
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