Increased Cellular Free Cholesterol in Macrophage-specific Abca1 Knock-out Mice Enhances Pro-inflammatory Response of Macrophages

Macrophage-specific Abca1 knock-out (Abca1(–)(M)(/–)(M)) mice were generated to determine the role of macrophage ABCA1 expression in plasma lipoprotein concentrations and the innate immune response of macrophages. Plasma lipid and lipoprotein concentrations in chow-fed Abca1(–)(M)(/–)(M) and wild-ty...

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Xuewei, Lee, Ji-Young, Timmins, Jenelle M., Brown, J. Mark, Boudyguina, Elena, Mulya, Anny, Gebre, Abraham K., Willingham, Mark C., Hiltbold, Elizabeth M., Mishra, Nilamadhab, Maeda, Nobuyo, Parks, John S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516976/
https://ncbi.nlm.nih.gov/pubmed/18552351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801408200
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