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Liver ABCA1 Deletion in LDLrKO Mice Does Not Impair Macrophage Reverse Cholesterol Transport or Exacerbate Atherogenesis

OBJECTIVE: Hepatic ATP binding cassette transporter A1 (ABCA1) expression is critical for maintaining plasma HDL concentrations, but its role in macrophage reverse cholesterol transport (RCT) and atherosclerosis is not fully understood. We investigated atherosclerosis development and RCT in hepatocy...

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Bibliographic Details
Main Authors: Bi, Xin, Zhu, Xuewei, Duong, MyNgan, Boudyguina, Elena Y., Wilson, Martha D., Gebre, Abraham K., Parks, John S.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793209/
https://ncbi.nlm.nih.gov/pubmed/23814116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301110
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