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A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea

Saccharopolyspora erythraea makes erythromycin, an antibiotic commonly used in human medicine. Unusually, the erythromycin biosynthetic (ery) cluster lacks a pathway-specific regulatory gene. We isolated a transcriptional regulator of the ery biosynthetic genes from S. erythraea and found that this...

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Detalhes bibliográficos
Main Authors: Chng, Chinping, Lum, Amy M., Vroom, Jonathan A., Kao, Camilla M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516264/
https://ncbi.nlm.nih.gov/pubmed/18685110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803622105
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