Engineering the Erythromycin-Producing Strain Saccharopolyspora erythraea HOE107 for the Heterologous Production of Polyketide Antibiotics

Bacteria of the genus Saccharopolyspora produce important polyketide antibiotics, including erythromycin A (Sac. erythraea) and spinosad (Sac. spinosa). We herein report the development of an industrial erythromycin-producing strain, Sac. erythraea HOE107, into a host for the heterologous expression...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Lü, Jin, Long, Qingshan, Zhao, Zhilong, Chen, Lu, He, Weijun, Hong, Jiali, Liu, Kai, Wang, Yemin, Pang, Xiuhua, Deng, Zixin, Tao, Meifeng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752772/
https://ncbi.nlm.nih.gov/pubmed/33363524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.593217
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