Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein.
We have isolated several mutant herpes simplex viruses, specifically mutated in the infected cell protein 8 (ICP8) gene, to define the functional domains of ICP8, the major viral DNA-binding protein. To facilitate the isolation of these mutants, we first isolated a mutant virus, HD-2, with the lacZ...
Enregistré dans:
| Publié dans: | J Virol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1989
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251191/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5258-5267.1989 |
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