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Conformational Changes in the Herpes Simplex Virus ICP8 DNA-Binding Protein Coincident with Assembly in Viral Replication Structures

The herpes simplex virus (HSV) single-stranded DNA-binding protein, ICP8, is required for viral DNA synthesis. Before viral DNA replication, ICP8 colocalizes with other replication proteins at small punctate foci called prereplicative sites. With the onset of viral genome amplification, these protei...

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Detalhes bibliográficos
Main Authors: Uprichard, Susan L., Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164794/
https://ncbi.nlm.nih.gov/pubmed/12805446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7467-7476.2003
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