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Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway

The role of herpes simplex virus ICP27 protein in mRNA export is investigated by microinjection into Xenopus laevis oocytes. ICP27 dramatically stimulates the export of intronless viral mRNAs, but has no effect on the export of cellular mRNAs, U snRNAs or tRNA. Use of inhibitors shows, in contrast t...

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Detalhes bibliográficos
Main Authors: Koffa, Maria D., Clements, J.Barklie, Izaurralde, Elisa, Wadd, Sarah, Wilson, Stuart A., Mattaj, Iain W., Kuersten, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125682/
https://ncbi.nlm.nih.gov/pubmed/11598019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5769
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