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Herpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway

The role of herpes simplex virus ICP27 protein in mRNA export is investigated by microinjection into Xenopus laevis oocytes. ICP27 dramatically stimulates the export of intronless viral mRNAs, but has no effect on the export of cellular mRNAs, U snRNAs or tRNA. Use of inhibitors shows, in contrast t...

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Autori principali: Koffa, Maria D., Clements, J.Barklie, Izaurralde, Elisa, Wadd, Sarah, Wilson, Stuart A., Mattaj, Iain W., Kuersten, Scott
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125682/
https://ncbi.nlm.nih.gov/pubmed/11598019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5769
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