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Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein.

We have isolated several mutant herpes simplex viruses, specifically mutated in the infected cell protein 8 (ICP8) gene, to define the functional domains of ICP8, the major viral DNA-binding protein. To facilitate the isolation of these mutants, we first isolated a mutant virus, HD-2, with the lacZ...

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Bibliografiske detaljer
Main Authors: Gao, M, Knipe, D M
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC251191/
https://ncbi.nlm.nih.gov/pubmed/2555553
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