Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.

We used indirect immunofluorescence to examine the factors determining the intranuclear location of herpes simplex virus (HSV) DNA polymerase (Pol) in infected cells. In the absence of viral DNA replication, HSV Pol colocalized with the HSV DNA-binding protein ICP8 in nuclear framework-associated st...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bush, M, Yager, D R, Gao, M, Weisshart, K, Marcy, A I, Coen, D M, Knipe, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847437/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1082-1089.1991
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