Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition.

Eucaryotic, viral, and bacteriophage DNA polymerases of the alpha-like family share blocks of sequence similarity, the most conserved of which has been designated region I. Region I includes a YGDTDS motif that is almost invariant within the alpha-like family and that is similar to a motif conserved...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Marcy, A I, Hwang, C B, Ruffner, K L, Coen, D M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2173770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.5883-5890.1990
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