The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes.

The early human papillomavirus type 16 genes that directly participate in the in vitro transformation of primary human keratinocytes have been defined. In the context of the full viral genome, mutations in either the E6 or E7 open reading frame completely abrogated transformation of these cells. Mut...

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Detaylı Bibliyografya
Asıl Yazarlar: Münger, K, Phelps, W C, Bubb, V, Howley, P M, Schlegel, R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC251060/
https://ncbi.nlm.nih.gov/pubmed/2476573
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