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Direct measurement of nitric oxide generation from nitric oxide synthase

Although nitric oxide synthase (NOS) is widely considered as the major source of NO in biological cells and tissues, direct evidence demonstrating NO formation from the purified enzyme has been lacking. It was recently reported that NOS does not synthesize NO, but rather generates nitroxyl anion (NO...

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Bibliographic Details
Main Authors: Xia, Yong, Zweier, Jay L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25093/
https://ncbi.nlm.nih.gov/pubmed/9356514
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