Properties of a simian virus 40 mutant T antigen substituted in the hydrophobic region: defective ATPase and oligomerization activities and altered phosphorylation accompany an inability to complex with cellular p53.

We have analyzed the biochemical properties of a nonviable simian virus 40 (SV40) mutant encoding a large T antigen (T) bearing an amino acid substitution (Pro-584-Leu) in its hydrophobic region. Mutant 5080 has an altered cell type specificity for transformation (transforming mouse C3H10T1/2 but no...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Tack, L C, Cartwright, C A, Wright, J H, Eckhart, W, Peden, K W, Srinivasan, A, Pipas, J M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250910/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2545911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.8.3362-3367.1989
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller