Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion

Vaccines harboring genes that encode functional oncoproteins are intrinsically hazardous, as their application may lead to introduction of these genes into normal cells and thereby to tumorigenesis. On the other hand, oncoproteins are especially attractive targets for immunotherapy of cancer, as the...

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Bibliografiska uppgifter
Huvudupphovsmän: Toes, René E. M., Hoeben, Rob C., van der Voort, Ellen I. H., Ressing, Maaike E., van der Eb, Alex J., Melief, Cornelis J. M., Offringa, Rienk
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC25085/
https://ncbi.nlm.nih.gov/pubmed/9405669
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