Loading...

Aphidicolin resistance in herpes simplex virus type 1 appears to alter substrate specificity in the DNA polymerase.

We describe novel mutants of herpes simplex virus which are resistant to aphidicolin. Their mutant phenotypes suggest that they encode DNA polymerases with altered substrate recognition. This conclusion is based on their abnormal sensitivity to polymerase inhibitors and to the abnormal mutation rate...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hall, J D, Woodward, S
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC250806/
https://ncbi.nlm.nih.gov/pubmed/2542598
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!