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ZEB1 Links Epithelial-Mesenchymal Transition and Cellular Senescence
Overexpression of zinc finger E-box binding homeobox transcription factor 1 (ZEB1) in cancer leads to epithelial-to-mesenchymal transition (EMT) and increased metastasis. As opposed to overexpression, we show that mutation of the ZEB1 gene in mice causes a mesenchymal-epithelial transition in gene e...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2507753/ https://ncbi.nlm.nih.gov/pubmed/18192284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.007047 |
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