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The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1

Although the involvement of protein arginine methyltransferase 1 (PRMT1) in tumorigenesis has been reported, its roles in breast cancer progression and metastasis has not been elucidated. Here we identified PRMT1 as a key regulator of the epithelial-mesenchymal transition (EMT) in breast cancer. We...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gao, Yanyan, Zhao, Yaping, Zhang, Juechao, Lu, Yang, Liu, Xin, Geng, Pengyu, Huang, Baiqu, Zhang, Yu, Lu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728496/
https://ncbi.nlm.nih.gov/pubmed/26813495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19874
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