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Developing microcolin A analogs as biological probes

Three microcolin A and B analogs have been synthesized. Their biological activity profiles were evaluated against several cell lines, revealing the existence of a structural determinant whose role in mediating the antiproliferative effect of the microcolins has heretofore gone unrecognized. While pr...

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Autors principals: Mandal, Amit K., Hines, John, Kuramochi, Kouji, Crews, Craig M.
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507739/
https://ncbi.nlm.nih.gov/pubmed/15993592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2005.06.020
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