A Role for Collagen IV Cross-links in Conferring Immune Privilege to the Goodpasture Autoantigen: STRUCTURAL BASIS FOR THE CRYPTICITY OF B CELL EPITOPES

The detailed structural basis for the cryptic nature (crypticity) of a B cell epitope harbored by an autoantigen is unknown. Because the immune system may be ignorant of the existence of such “cryptic” epitopes, their exposure could be an important feature in autoimmunity. Here we investigated the s...

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Detalhes bibliográficos
Main Authors: Vanacore, Roberto M., Ham, Amy-Joan L., Cartailler, Jean-Philippe, Sundaramoorthy, Munirathinam, Todd, Parvin, Pedchenko, Vadim, Sado, Yoshikazu, Borza, Dorin-Bogdan, Hudson, Billy G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504875/
https://ncbi.nlm.nih.gov/pubmed/18499662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803451200
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