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Goodpasture’s Disease: molecular architecture of the autoantigen provides clues to etiology and pathogenesis
PURPOSE OF REVIEW: Goodpasture’s (GP) disease is an autoimmune disorder characterized by the deposition of pathogenic autoantibodies in basement membranes of kidney and lung, which induces rapidly progressive glomerulonephritis and pulmonary hemorrhage. The target antigen is the α3NC1 domain of coll...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159420/ https://ncbi.nlm.nih.gov/pubmed/21378566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0b013e328344ff20 |
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