A Role for Collagen IV Cross-links in Conferring Immune Privilege to the Goodpasture Autoantigen: STRUCTURAL BASIS FOR THE CRYPTICITY OF B CELL EPITOPES

The detailed structural basis for the cryptic nature (crypticity) of a B cell epitope harbored by an autoantigen is unknown. Because the immune system may be ignorant of the existence of such “cryptic” epitopes, their exposure could be an important feature in autoimmunity. Here we investigated the s...

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Hlavní autoři: Vanacore, Roberto M., Ham, Amy-Joan L., Cartailler, Jean-Philippe, Sundaramoorthy, Munirathinam, Todd, Parvin, Pedchenko, Vadim, Sado, Yoshikazu, Borza, Dorin-Bogdan, Hudson, Billy G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504875/
https://ncbi.nlm.nih.gov/pubmed/18499662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803451200
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