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Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

Brain arteriovenous malformations (BAVMs) can cause devastating stroke in young people and contribute to half of all hemorrhagic stroke in children. Unfortunately, the pathogenesis of BAVMs is unknown. In this article we show that activation of Notch signaling in the endothelium during brain develop...

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Bibliographic Details
Main Authors: Murphy, Patrick A., Lam, Michael T. Y., Wu, Xiaoqing, Kim, Tyson N., Vartanian, Shant M., Bollen, Andrew W., Carlson, Timothy R., Wang, Rong A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504798/
https://ncbi.nlm.nih.gov/pubmed/18667694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802743105
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