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Notch4 is activated in endothelial and smooth muscle cells in human brain arteriovenous malformations

Up-regulation of Notch4 was observed in the endothelial cells in the arteriovenous malformations (AVMs) in mice. However, whether Notch4 is also involved in brain AVMs in humans remains unclear. Here, we performed immunohistochemistry on normal brain vascular tissue and surgically resected brain AVM...

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Bibliografiske detaljer
Main Authors: ZhuGe, Qichuan, Wu, Zhebao, Huang, Lijie, Zhao, Bei, Zhong, Ming, Zheng, WeiMing, GouRong, Chen, Mao, XiaoOu, Xie, Lin, Wang, Xiangdong, Jin, Kunlin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877925/
https://ncbi.nlm.nih.gov/pubmed/24373503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12115
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