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Notch4 is activated in endothelial and smooth muscle cells in human brain arteriovenous malformations

Up-regulation of Notch4 was observed in the endothelial cells in the arteriovenous malformations (AVMs) in mice. However, whether Notch4 is also involved in brain AVMs in humans remains unclear. Here, we performed immunohistochemistry on normal brain vascular tissue and surgically resected brain AVM...

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Hlavní autoři: ZhuGe, Qichuan, Wu, Zhebao, Huang, Lijie, Zhao, Bei, Zhong, Ming, Zheng, WeiMing, GouRong, Chen, Mao, XiaoOu, Xie, Lin, Wang, Xiangdong, Jin, Kunlin
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877925/
https://ncbi.nlm.nih.gov/pubmed/24373503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12115
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