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Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels
Arteriovenous (AV) malformation (AVM) is a devastating condition characterized by focal lesions of enlarged, tangled vessels that shunt blood from arteries directly to veins. AVMs can form anywhere in the body and can cause debilitating ischemia and life-threatening hemorrhagic stroke. The mechanism...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273347/ https://ncbi.nlm.nih.gov/pubmed/25468970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415316111 |
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