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Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice

Brain arteriovenous malformations (BAVMs) can cause devastating stroke in young people and contribute to half of all hemorrhagic stroke in children. Unfortunately, the pathogenesis of BAVMs is unknown. In this article we show that activation of Notch signaling in the endothelium during brain develop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Murphy, Patrick A., Lam, Michael T. Y., Wu, Xiaoqing, Kim, Tyson N., Vartanian, Shant M., Bollen, Andrew W., Carlson, Timothy R., Wang, Rong A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504798/
https://ncbi.nlm.nih.gov/pubmed/18667694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802743105
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