Strain-Specific Spontaneous and NNK-Mediated Tumorigenesis in Pten+/- Mice

Pten is a negative regulator of the Akt pathway, and its inactivation is believed to be an etiological factor in many tumor types. Pten+/- mice are susceptible to a variety of spontaneous tumor types, depending on strain background. Pten+/- mice, in lung tumor-sensitive and -resistant background str...

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Hlavní autoři: Hollander, Mary Christine, Balogh, Andria R, Liwanag, Jaminelli, Han, Wei, Linnoila, Ritva Ilona, Anver, Miriam R, Dennis, Phillip A
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504769/
https://ncbi.nlm.nih.gov/pubmed/18683321
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