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Ku80 removal from DNA through double strand break–induced ubiquitylation
The Ku70/Ku80 heterodimer, or Ku, is the central component of the nonhomologous end joining (NHEJ) pathway of double strand break (DSB) repair. Because Ku forms a ring through which the DSB threads, it likely becomes topologically attached to DNA during repair. The mechanism for its removal was unkn...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2500133/ https://ncbi.nlm.nih.gov/pubmed/18678709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200802146 |
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