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In vitro selection for altered divalent metal specificity in the RNase P RNA
The ribozyme RNase P absolutely requires divalent metal ions for catalytic function. Multiple Mg(2+) ions contribute to the optimal catalytic efficiency of RNase P, and it is likely that the tertiary structure of the ribozyme forms a specific metal-binding pocket for these ions within the active-sit...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences of the USA
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24975/ https://ncbi.nlm.nih.gov/pubmed/9405616 |
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