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In vitro selection for altered divalent metal specificity in the RNase P RNA

The ribozyme RNase P absolutely requires divalent metal ions for catalytic function. Multiple Mg(2+) ions contribute to the optimal catalytic efficiency of RNase P, and it is likely that the tertiary structure of the ribozyme forms a specific metal-binding pocket for these ions within the active-sit...

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Sonraí Bibleagrafaíochta
Main Authors: Frank, Daniel N., Pace, Norman R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences of the USA 1997
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC24975/
https://ncbi.nlm.nih.gov/pubmed/9405616
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