Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21

The fibroblast growth factor (FGF) 19 subfamily of ligands, FGF19, FGF21, and FGF23, function as hormones that regulate bile acid, fatty acid, glucose, and phosphate metabolism in target organs through activating FGF receptors (FGFR1–4). We demonstrated that Klotho and βKlotho, homologous single-pas...

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Autori principali: Kurosu, Hiroshi, Choi, Mihwa, Ogawa, Yasushi, Dickson, Addie S., Goetz, Regina, Eliseenkova, Anna V., Mohammadi, Moosa, Rosenblatt, Kevin P., Kliewer, Steven A., Kuro-o, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496965/
https://ncbi.nlm.nih.gov/pubmed/17623664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704165200
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