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Protein Kinase A (PKA) Isoform RII(β) Mediates the Synergistic Killing Effect of cAMP and Glucocorticoid in Acute Lymphoblastic Leukemia Cells
Protein kinase A (PKA) or cAMP-dependent protein kinase (cAPK) mediates the synergistic effects of cAMP- and glucocorticoid (GC)-induced apoptosis in lymphoid cells. Using two human acute lymphoblastic leukemia cell (CEM) clones with respective GC-sensitive and GC-resistant phenotypes, we discovered...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494930/ https://ncbi.nlm.nih.gov/pubmed/18544528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803193200 |
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