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Cystic Fibrosis Transmembrane Regulator Missing the First Four Transmembrane Segments Increases Wild Type and ΔF508 Processing
We previously generated an adenoassociated viral gene therapy vector, rAAV-Δ264 cystic fibrosis transmembrane conductance regulator (CFTR), missing the first four transmembrane domains of CFTR. When infected into monkey lungs, Δ264 CFTR increased the levels of endogenous wild type CFTR protein. To u...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494918/ https://ncbi.nlm.nih.gov/pubmed/18508776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709156200 |
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