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Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7

Systemic viral infections produce a highly regulated set of responses in sickness behavior, such as fever, anorexia, and adipsia. Toll-like receptor (TLR)7, activated by viral RNA during infection, potently stimulates the innate and adaptive immune responses that aid in viral clearance. However, the...

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Autori principali: Hayashi, Tomoko, Cottam, Howard B., Chan, Michael, Jin, Guangyi, Tawatao, Rommel I., Crain, Brian, Ronacher, Lisa, Messer, Karen, Carson, Dennis A., Corr, Maripat
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494819/
https://ncbi.nlm.nih.gov/pubmed/18480244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00527.2007
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