Role of the Transcription Factor Sox4 in Insulin Secretion and Impaired Glucose Tolerance

OBJECTIVES— To identify, map, clone, and functionally validate a novel mouse model for impaired glucose tolerance and insulin secretion. RESEARCH DESIGN AND METHODS— Haploinsufficiency of the insulin receptor and associated mild insulin resistance has been used to sensitize an N-ethyl-N-nitrosourea...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Goldsworthy, Michelle, Hugill, Alison, Freeman, Helen, Horner, Emma, Shimomura, Kenju, Bogani, Debora, Pieles, Guido, Mijat, Vesna, Arkell, Ruth, Bhattacharya, Shoumo, Ashcroft, Frances M., Cox, Roger D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2008
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494690/
https://ncbi.nlm.nih.gov/pubmed/18477811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-0337
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge